Pain in Cats: Signs, Causes, & Treatment

Cat Center

How do you know if your cat is in pain? Most owners think they’d be a great judge. Unfortunately, the truth is less comforting than we’d like.

Not only are cat parents poor judges of pain in their furry family, veterinarians have historically been equally oblivious to the discomforts of the feline species. We’ve only recently begun to suspect the true depths of pain and discomfort cats can feel – all without showing any obvious sign.

If their pain is so hard to identify, how do we know they’re really experiencing pain? Turns out we use many of the same indicators used in pediatric medicine to assess infant pain, which is a nifty trick that’s especially helpful when it comes to treating pain in cats. Except that pain in cats can be tricky.

Signs of Pain in Cats

There are many ways felines attempt to hide their discomfort, but the signs can be broken down into two categories:

  1. Behavioral

  2. Physical

As previously stated, pain in cats is a tough thing to assess. Their silent stoicism, while admirable, doesn’t exactly lend itself to easy interpretation in the event of pain. Even severe pain often goes undiagnosed in cats.

There are some behavioral characteristics cats present that are now associated with post-operative pain in felines. It seems we’re getting smarter on this issue. Some behavioral differences that indicate pain include

  • Excessive Sleeping

  • Avoiding Movement

  • Isolation from Family

  • General Change in Attitude

If your happy-go-lucky cat who loves to snuggle suddenly is defensive and keeping to themselves, that is a big sign that something is off.

Physical signs range from:

  • Limping[KB2]

  • Licking Paws

  • Changes in


  • Changes in Appetite

  • & More

What causes pain in cats?

Here are seven painful conditions my feline-owning clients often overlook:

1. Ingrown Claws

This happens when especially curly claws don’t get trimmed. It is most common in older cats whose claws tend to grow thicker and longer due to their more limited exercise. Trimming your cat’s nails can help to prevent this.

Look for: Limping, licking paws, and walking around less, especially on harder surfaces.

2. Feline Idiopathic Cystitis

This inflammatory bladder disease is considered highly painful. Thankfully, many cats demonstrate their discomfort, usually by urinating about the house (often while straining).

Look for: Going in and out of the litterbox more often than usual and urinating in small volumes (sometimes you can tell, depending on the kind of litter you use).

3. Periodontal Disease

Cats afflicted with periodontal disease typically do not show signs of having painful teeth and gums. Even when cavity-like lesions (feline resorptive lesions) painfully expose the pulp of their teeth, cats will act as if nothing’s wrong.

Look for: Reduction in appetite, a messy feeding area (they often move their head erratically as they painfully ingest their food), eating with their head to one side, taking longer to eat than usual, regurgitating dry food (because they’re not chewing it), and exhibiting a preference for one kind of food over another (not necessarily wet over dry).

4. Stomatitis

This inflammatory condition of the mouth is kind of like periodontal disease, only more sudden and more painful. But still, we tend to overlook it. While there are not many options for limiting pain associated with stomatitis, there are procedures to help remedy stomatitis in cats.

Look for: Drooling, staring at the food bowl as if hungry but unwilling to eat, head shaking, a less groomed appearance (most won’t groom as much), and sometimes even yowling when eating.

5. Osteoarthritis

Some researchers have suggested that the incidence of osteoarthritis in cats is higher than in dogs,  which probably comes as a surprise to those of you who had no idea cats could even get arthritis.

Look for: Decreased overall activity, less jumping (especially on higher surfaces), and, only rarely, limping.

6. Otitis

Ear pain happens when chronic skin disease of the external ear canal leads to infection and ulceration we call otitis. One or both ears may be affected.

Look for: Head shaking, scabs from scratching around the head and face, holding the head to one side, hair loss around the ears.

7. Ocular Disease

Ever seen your cat squint at you with one eye? More than likely they were experiencing some degree of ocular discomfort. Corneal ulceration, where the cornea is injured, is perhaps the most severely painful, but cats suffer more commonly from uncomfortable viral infections of the tissues surrounding the eyes, such as conjunctivitis. This can occur in one of both eyes.

Look for:  Squinting, ocular discharge, weepy eyes, red or swollen eyes or lids. Embrace covers dental illnessesalternative therapies for arthritis, and more in order to keep your beloved pet as comfortable as possible.

How to Treat Pain in Cats

Pain relief, in particular, is a surprisingly frustrating issue in feline medicine. Few reasonable alternatives to long term pain control in cats exist. So, while severe acute or post-op pain can be managed with heavy-duty narcotics (strong opiates like hydromorphone), there’s little available to treat long term illnesses, such as osteoarthritis.

Still, pain relief in cats has come a long way over the last couple of decades. It’s now become clear that to deny a patient a pain control drug on the basis of "safety" may not make so much sense if the patient’s degree of pain is significant. The impact of severe pain on the patient’s long term well-being is now considered in a more "holistic" manner. And that’s undoubtedly a good thing.

But the sad truth remains that few drugs are available for certain kinds of pain. Transdermal fentanyl patches, tramadol, and butorphanol are all opiates that are used for acute and sub-acute pain control (as in an end-of life hospice setting). But for more chronic pain control (for arthritis, for example), these drugs are typically considered too life altering. But not for all – sometimes it is worth a try to see how an individual cat will react.

In terms of options for chronic pain, there have been attempts to identify NSAIDs that cats will tolerate. This class of drug has been responsible for much of the chronic pain control in dogs and humans over the past few decades.

However, NSAIDs have been tricky since gastrointestinal and renal side effects are much more common with NSAIDs when used in cats. Though we will tap these meds for their anti-inflammatory effects, we tend to do so only in well-hydrated cats whose renal status is consistently normal – and typically only for a short period of time.

Prescription Medications to Treat Pain in Cats


Metacam (meloxicam) is one such drug whose one-dose injectable formulation is approved by the FDA for use in cats. But it’s not for those who suffer chronic pain, as in the case of arthritis, or slow-moving cancers that require some anti-inflammatory palliation. In fact, a recent FDA labeling advisory cautioned us strongly against the use of oral Metacam for long-term care as it’s just too toxic to the kidneys


Onsior (robenacoxib) is another, but it’s only approved for three short days’ use.

Here are other NSAIDs that are sometimes used instead:

  • Aspirin

  • Ketoprofen

  • Ketorolac tromethamine

  • Carprofen (Rimadyl)

It is suggested to use these options with caution. Always remember that there is no "one size fits all" in medicine, even less so when it comes to controlling pain – and nowhere is this more true than when trying hard to control pain in cats.

If your cats have been diagnosed with any of the above conditions, definitely ask your veterinarian for progressive pain control measures.